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Sample filtration using syringe filters containing 0.45 μm (HPLC) or 0.2 μm (UHPLC) pore size membranes will also extend the life of chromatography columns by preventing particulate from blocking the flow path between the column packing. PVDF syringe filters offer excellent chemical compatibility, including aggressive acids and alcohols.
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Syringe filters with different pore size ratings are suitable for different applications. For example, syringe filters containing 0.45 μm are typically used for HPLC sample preparation and 0.2 μm is used for UHPLC. In life science applications 0.1 and 0.2 µm pore sizes provide sterilization of buffers, culture media, and additives.
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